论文、专利与项目 Publications, Patents and Grants

Dacheng Ma, Zhimeng Xu, Zhaoyu Zhang, Xi Chen, Xiangzhi Zeng, Yiyang Zhang, Tingyue Deng et al. "Engineer chimeric Cas9 to expand PAM recognition based on evolutionary information." Nature Communications 10, no. 1 (2019): 560.

Dacheng Ma#, Shuguang Peng#, and Zhen Xie. "Integration and exchange of split dCas9 domains for transcriptional controls in mammalian cells." Nature Communications 7, no. 1 (2016): 13056.

Dacheng Ma#, Qichen Yuan#, Fei Peng#, Victor Paredes, Hongzhi Zeng, Emmanuel C. Osikpa, Qiaochu Yang et al. "Engineered PROTAC-CID systems for mammalian inducible gene regulation." Journal of the American Chemical Society 145, no. 3 (2023): 1593-1606.

Dacheng Ma, Shuguang Peng, Weiren Huang, Zhiming Cai, and Zhen Xie. "Rational design of mini-Cas9 for transcriptional activation." ACS Synthetic Biology 7, no. 4 (2018): 978-985.

Guo, Tingxi#, Dacheng Ma#, and Timothy K. Lu. "Sense-and-respond payload delivery using a novel antigen-inducible promoter improves suboptimal CAR-T activation." ACS Synthetic Biology 11, no. 4 (2022): 1440-1453.

Xu, Zhimeng, Dacheng Ma, Houzhen Su, Xiaodong Jia, Yinqing Li, Yinying Lu, and Zhen Xie. "Explore the dominant factor in prime editing via a view of DNA processing." Synthetic and Systems Biotechnology 8, no. 3 (2023): 371-377.

Zeng, Hongzhi, Qichen Yuan, Fei Peng, Dacheng Ma, Ananya Lingineni, Kelly Chee, Peretz Gilberd, Emmanuel C. Osikpa, Zheng Sun, and Xue Gao. "A split and inducible adenine base editor for precise in vivo base editing." Nature Communications 14, no. 1 (2023): 5573.

Guo, Jianying, Dacheng Ma, Rujin Huang, Jia Ming, Min Ye, Kehkooi Kee, Zhen Xie, and Jie Na. "An inducible CRISPR-ON system for controllable gene activation in human pluripotent stem cells." Protein & cell 8, no. 5 (2017): 379-393.

Liu, Xinyue, Yueying Yang, Maria Eugenia Inda, Shaoting Lin, Jingjing Wu, Yoonho Kim, Xiaoyu Chen, Dacheng Ma, Timothy K. Lu, and Xuanhe Zhao. "Magnetic living hydrogels for intestinal localization, retention, and diagnosis." Advanced Functional Materials 31, no. 27 (2021): 2010918.

Guo, Yucheng, Chen Bao, Dacheng Ma, Yubing Cao, Yanda Li, Zhen Xie, and Shao Li. "Network-based combinatorial CRISPR-Cas9 screens identify synergistic modules in human cells." ACS Synthetic Biology 8, no. 3 (2019): 482-490.